Amyloidosis is a rare and serious condition characterized by the abnormal buildup of amyloid proteins in various tissues and organs, often leading to significant health challenges. Recognizing early warning signs is crucial, as timely diagnosis and intervention can substantially enhance patient outcomes and quality of life. This guide is designed to help individuals identify symptoms like fatigue, swelling, and unexplained weight loss, which may indicate the presence of amyloidosis. Understanding these signs and seeking prompt medical advice can be pivotal in managing the disease effectively.